Table 2.

Characteristics of the control persons and patients whose lung tissues were used for the immunohistochemistry

	Subject Groups
	Control	COPD Stage II	COPD Stage IV
Number of subjects	10	8	9
Age, yr	67 (55–74)	71* (58–80)	58‡ (50–66)
Male/female	4/6	6/2	3/6
Pack yr	15 (1.5–65)2+	36.5 (10–44)+	26 (18–38)+
FEV1% predicted	97.1 (63.7–121)2+	65* (41.7–71)+	20.6†§ (13–36)
FEV1/FVC	73.6 (64–86.2)+	63† (45.7–64.1)+	36.8†‡ (25–66)

All values except number of subjects and sex are expressed as median values with minimum and maximum range in parentheses. Only ex-smokers were included.

^*P < 0.05,

^†P < 0.001 compared with control group,

^‡P < 0.05,

^§P < 0.001 compared with COPD stage II (Mann-Whitney U-test). ⁺1 data point unknown, ²⁺2 data points unknown.