Table 1.

ET-1 inhibition of Na⁺ transporters along the nephron.

Proximal Tubule	NHE3, Na⁺/K⁺ ATPase,	ET_B, ET_A?	^{3, 4, 6, 10}
Thin Limb
Thick ascending Loop	Na⁺/K⁺/2Cl⁻, Na⁺/K⁺ ATPase	ET_B	^{22, 24}
Cortical Collecting Duct	Na⁺/K⁺ ATPase, ENaC	ET_A, ET_B	^{30, 60}
Inner Medullary CD	Na⁺/K⁺ ATPase, ENaC?	ET_A, ET_B	³