Table 2.

Skeletal muscle endothelial responses of KO and WT mice after 8 weeks of HFD vs. chow

Genbank accession	Gene name	WT H/C	KO H/C
NM_008491	lipocalin 2	−1.23	−2.06
NM_011784	apelin receptor	1.56	1.52
NM_009325	thromboxane A2 receptor	1.78	1.74
NM_019985	C-type lectin domain family 1, member b	0.64	−1.03
BC007177	cyclin L1	−0.06	−1.15
NM_010104	endothelin 1	−0.48	−1.15
AK042211	endothelin receptor type A	−0.85	−1.44
NM_009605	adiponectin, C1Q and collagen domain containing	0.26	−1.16
NM_021896	guanylate cyclase 1, soluble, alpha 3	−1.31	−1.16
NM_009694	apolipoprotein B mRNA editing enzyme, catalytic polypeptide	0.58	−1.18
NM_026672	glutathione S-transferase, mu 7	−0.75	−1.32
NM_007413	adenosine A2b receptor	−0.49	−1.35
NM_177687	cAMP responsive element binding protein-like 2	−1.23	−1.67
NM_008161	glutathione peroxidase 3	−1.84	−1.68
NM_053247	lymphatic vessel endothelial hyaluronan receptor 1	0.90	−1.20
NM_009805	CASP8 and FADD-like apoptosis regulator	0.39	−1.02
NM_013459	complement factor D (adipsin)	−1.77	−3.65
NM_009928	collagen, type XV, alpha 1	2.59	2.27
NM_011607	tenascin C	2.00	1.11
NM_021281	cathepsin S	3.30	1.45
X70100	fatty acid binding protein 5, epidermal	1.47	0.94
L38613	glucagon receptor	1.39	0.17
J05020	Fc receptor, IgE, high affinity I	1.37	1.15
NM_011311	S100 calcium binding protein A4	1.30	2.01
NM_008332	interferon-induced protein with tetratricopeptide repeats 2	1.05	0.50
NM_008329	interferon activated gene 204	1.18	0.65
NM_008620	guanylate binding protein 4	1.05	0.52
AK087208	endothelial PAS domain protein 1	−1.06	−0.78
NM_178020	hyaluronoglucosaminidase 3	−1.11	−0.20
AK032692	immediate early response 2	−1.18	−0.36
AK163452	aldehyde dehydrogenase 2, mitochondrial	−1.33	−0.55
NM_133808	high density lipoprotein (HDL) binding protein	−0.57	0.05
NM_027286	Angiotensin I converting enzyme	−1.36	−0.58

Transcripts shown are dysregulated >1log₂ [fold change] in either KO or WT compared to their respective chow-fed controls