Table 1.
Demographic characteristics of total population and distinguished subgroups
| Nonstandard treatment (N = 142)* | |||
|---|---|---|---|
| Total population (N = 829) | Proposed by the MDT (N = 89) | Desired by the patient (N = 60) | |
| Age (years) (mean and standard deviation) | 63.9 (11.1) | 67.2 (10.9) | 71.2 (12.2) |
| Gender | |||
| Male | 596 (72 %) | 69 (78 %) | 32 (53 %) |
| Female | 233 (28 %) | 20 (22 %) | 28 (47 %) |
| Comorbidity score (ACE-27) | |||
| 0 | 182 (22 %) | 3 (3 %) | 11 (18 %) |
| 1 | 327 (39 %) | 30 (34 %) | 18 (30 %) |
| 2 | 239 (29 %) | 36 (40 %) | 22 (37 %) |
| 3 | 81 (10 %) | 20 (23 %) | 9 (15 %) |
| Tumor stage | |||
| 1 | 162 (20 %) | 5 (6 %) | 8 (13 %) |
| 2 | 180 (22 %) | 6 (7 %) | 7 (12 %) |
| 3 | 161 (19 %) | 26 (29 %) | 7 (12 %) |
| 4 | 326 (39 %) | 52 (58 %) | 38 (63 %) |
| Tumor site | |||
| Lip | 24 (3 %) | 0 (0 %) | 1 (1 %) |
| Nasopharynx | 29 (4 %) | 4 (4 %) | 25 (42 %) |
| Oral cavity | 255 (31 %) | 17 (19 %) | 17 (29 %) |
| Oropharynx | 213 (26 %) | 27 (30 %) | 6 (10 %) |
| Supraglottic larynx | 89 (11 %) | 13 (15 %) | 3 (5 %) |
| Glottic larynx | 124 (15 %) | 8 (9 %) | 8 (13 %) |
| Hypopharynx | 95 (11 %) | 20 (23 %) | 0 (0 %) |
| Prior malignancy | |||
| No | 669 (81 %) | 70 (79 %) | 47 (78 %) |
| Other prior cancer yet treated | 84 (10 %) | 7 (8 %) | 8 (13 %) |
| Prior head and neck cancer yet treated | 76 (9 %) | 12 (13 %) | 5 (9 %) |
| Marital status | |||
| Partner | 569 (69 %) | 50 (56 %) | 27 (45 %) |
| Single | 260 (31 %) | 39 (44 %) | 33 (55 %) |
| Standard treatment according to guidelines | |||
| Radiotherapy | 185 (22 %) | 10 (11 %) | 4 (7 %) |
| Chemoradiation | 183 (22 %) | 47 (53 %) | 14 (23 %) |
| Surgery + radiotherapy | 208 (25 %) | 20 (22 %) | 29 (48 %) |
| Surgery + chemotherapy | 12 (1 %) | 3 (3 %) | 0 (0 %) |
| Surgery + postoperative radiation (PORT) on indication | 116 (14 %) | 4 (5 %) | 7 (12 %) |
| Surgery | 125 (15 %) | 5 (6 %) | 6 (10 %) |
| Year of treatment | |||
| 2010 | 234 (28 %) | 27 (30 %) | 21 (35 %) |
| 2011 | 259 (31 %) | 22 (25 %) | 21 (35 %) |
| 2012 | 335 (41 %) | 40 (45 %) | 18 (30 %) |
*In seven patients, both MDT and patient were non-compliant to standard treatment guidelines; patients received a proposal of nonstandard treatment by the MDT but however refused any treatment