Table 3.

Unadjusted and adjusted OR’s for patient decisions to choose nonstandard treatment and adjusted OR’s after stratification for gender

		Not stratified analysis				Stratification for gender
Characteristic		OR unadjusted	95 % CI	OR adjusted b	95 % CI	♂OR adjusted c	95 % CI	♀OR adjusted c	95 % CI
Age	<65 years a	3.19*	1.8–5.7	3.40*	1.8–6.4	1.73	0.8–3.6	7.22*	2.4–22.1
	≥65 years
Gender	Male a	2.41*	1.4–4.1	2.66*	1.5–4.8	-	-	-	-
	Female
Comorbidity score (ACE-27)	Low (0–1) a	1.78*	1.0–3.0	1.49	0.8–2.7	1.77	0.8–3.7	1.39	0.6–3.3
	High (2–3)
Tumor stage	Early (I-II) a	2.22*	1.2–4.1	1.07	0.4–2.9	2.88*	1.2–7.1	1.92	0.8–4.7
	Advanced (III-IV)
Tumor site	Oral cavity a					-	-	-	-
	Pharynx	0.78	0.4–1.4	1.34	0.6–3.0
	Larynx	0.43*	0.2–0.9	0.82	0.3–2.1
Prior malignancy	No a					-	-	-	-
	Other prior cancer yet treated	1.39	0.6–3.1	1.09	0.5–2.6
	Prior head and neck cancer yet treated	0.93	0.4–2.4	0.99	0.3–2.9
Marital status	Partner a	2.92*	1.7–5.0	2.25*	1.2–4.1	1.64	0.8–3.5	3.63*	1.5–9.0
	Single
Children	Yes a					-	-	-	-
	No	2.26*	1.3–4.1	2.08*	1.0–4.1
	Unknown	0.78	0.3–1.8	1.19	0.5 3.0
	No contact	1.66	0.4–7.5	1.19	0.2–5.9
Standard treatment according to guidelines	Surgery a					-	-	-	-
	Radiotherapy	0.44	0.1–1.6	0.29	0.07–1.2
	Chemoradiation	1.64	0.6–4.4	1.15	0.3–4.6
	Surgery + radiotherapy	3.21*	1.3–8.0	2.16	0.6–7.6
	Surgery + chemotherapy	-	-	-	-
	Surgery + PORT on indication	1.27	0.4–3.9	1.10	0.3–3.8
Year of treatment	2010 a					-	-	-	-
	2011	0.89	0.5–1.7	0.73	0.4–1.5
	2012	0.57	0.3–1.1	0.63	0.3–1.3

^a = reference value, ^b = odds ratio calculated using multivariate logistic regression analysis adjusting for age, gender, comorbidity, tumor stage, tumor site, prior malignancy, marital status, having children, standard treatment proposal according to guidelines, year of treatment, ^c = odds ratio stratified for gender (male versus female) calculated using multivariate logistic regression analysis adjusting for age, comorbidity, tumor stage and marital status, * = p value < 0.05