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Association of the NASH severity score (NAS+Fibrosis severity scores) with morphine glucuronide Cmax (A) and AUC0-last (B). Values for patients with NASH (triangles) and for healthy subjects (circles) are shown with the linear regression and its 95% confidence limits (shaded area). The NASH severity score is the sum of the NAS and fibrosis biopsy scores; for healthy subjects, an imputed value of zero was assumed.
