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. Author manuscript; available in PMC: 2016 May 1.
Published in final edited form as: Crit Care Med. 2015 May;43(5):1102–1111. doi: 10.1097/CCM.0000000000000852

TABLE 1.

Trials Reporting on ICU Admissions

Author
(Reference)
Year Type of
Study
Sample Size: for
RCT, Number
Randomized to
Intervention
(Control); for
Non-RCT, Number
in Each Group
Sample Size for
ICU Admissions
Outcome: Intervention
(Control)
Data Quality
(Monitored
Accuracy or
Reliability)
Primary
Outcome
Measures
Prespecified
Percent
Randomized
to Intervention
Who Received
Intervention
Gade et al (23) 2008 RCT 280 (237) 230 (218) Yes Yes 98.2
Penrod et al (16) 2006 Retrospective, observational 82 (232) 82 (232) No Yes NA
Penrod et al (17) 2010 Retrospective, observational 606 (2715) 824 (5,771)a No Yes NA

RCT = randomized controlled trial, NA = not applicable.

a

Represents number of hospitalizations.