Table 5.
Estimates of Intervention Effect Size
| Category | Percent Relative Risk Reductiona |
|---|---|
| Trials reporting on ICU admissions (n = 3) | |
| Mean (sd) | 37 (23) |
| Median (IQR) | 50 (11, 51) |
| Trials reporting on ICU length of stay | |
| Intervention in acute care setting (n = 1) | 52 |
| Intervention in outpatient setting (n = 1) | No change |
| Intervention in ICU settingb (n = 14) | |
| Mean (sd) | 26 (23) |
| Median (IQR) | 22 (48, 0) |
| Intervention in ICU setting restricted to patient/provider targets (n = 10) | |
| Mean (sd) | 33 (23) |
| Median (IQR) | 33 (49, 18) |
IQR = interquartile range.
a
Mean relative risk reduction value used from each trial except for Lilly trial (33), which only reported a median reduction in length of stay.
b
For trials with separate values for survivors and decedents, we selected the relative risk reduction for decedents.