Table 1.
Group | NF-κB p65 |
---|---|
Vehicle + control group | 0.026 ± 0.006 |
Vehicle + MSU crystal | 0.097 ± 0.022++ |
MSU + indomethacin (3 mg/kg) | 0.047 ± 0.013∗∗ |
MSU + PRP15 (0.4 g/kg) | 0.046 ± 0.003∗∗ |
MSU + PRP15 (0.8 g/kg) | 0.038 ± 0.013∗∗ |
MSU + PRP15 (1.2 g/kg) | 0.036 ± 0.016∗∗ |
For quantitation, 30 visual fields were analyzed from each group, five from each of the six sections from separate rats. From these, the MOD values were calculated. MOD: mean optical density. Data are means ± SD (n = 6). ++ P < 0.01 versus vehicle-control group (control). ∗∗ P < 0.01 versus vehicle with MSU crystal (model).