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. 2015 Winter;14(Suppl):23–31.

Table 2.

Physicochemical characterization of Diclofenac Na ocular films.

Formulation Weight (mg) Thickness (µm) Drug content (%) Swelling index (%)
A1 10.33 ± 0.76 75 ± 5 100.63 ± 0.65 705 ± 11.4
A2 11.60 ± 0.37 85 ± 5 98.5 ± 0.54 598 ± 6.1
A3 12.36 ± 0.55 93 ± 5.77 101. 90 ± 0.80 412 ± 5.67
B1a 20.96 ± 0.15 148. 33 ± 2.88 99.00 ± 0.59 750 ± 8.9
B1b 21.36 ± 1.48 175.00 ± 8.02 98.75 ± 0.67 1110 ± 13.4
B1c 11.93 ± 0.40 126. 00 ± 3.73 100.06 ± 0.70 1117 ±14.2
B2a 18.93 ± 1.33 133.00 ± 5.77 98.12 ± 0.80 610 ± 7.9
B2b 14.26 ± 1.10 116 ± 4.32 99.96 ± 0.49 1580 ± 16.8
C1a 13.55 ± 0.25 100.00 ± 5.5 96.9 ± 0.96 799 ± 6.8
C1b 14.23 ± 0.02 105.00 ± 8.66 98.63 ± 0.84 761 ± 5.9
C1c 14.5 ± 1.85 113.00 ± 10.40 98.97 ± 0.99 520 ± 4.6
C1d 16.76 ± 1.26 118.00 ± 7.63 102.10 ± 0.76 601 ± 5.1
C2a 11.46 ± 1.10 95.50 ± 5.00 98.55 ± 0.27 608 ± 6.2
C2b 16.52 ± 0.56 120.00 ± 0.01 99.99 ± 0.76 592 ± 6.9
C2c 13.83 ± 0.20 113.30 ± 2.80 99.97 ± 0.89 589 ± 4.9
C3a 10.20 ± 0.41 88.33 ± 5.77 98.43 ± 0.07 445 ± 5.5
C3b 14.76 ± 0.65 115.00 ± 5.00 97.56 ± 0.55 454 ± 4.8
D1a 10.00 ± 0.95 85.00 ± 10.00 98.50 ± 0.11 690 ± 7.9
D1b 11.20 ± 1.05 91.66 ± 2.88 98.86 ± 0.49 601 ± 6.8
D1c 12.46 ± 1.07 98.33 ± 7.63 99.80 ± 0.98 580 ± 5.8
D2a 17.20 ± 0.84 115.00 ± 5.00 102.05 ± 0.87 501 ± 4.9
D2b 17.76 ± 0.59 141.00 ± 4.18 99.12 ± 0.15 578 ± 5.1
D2c 18.66 ± 1.15 150.00 ± 0.00 98.98 ± 0.23 703 ± 5.6
D3a 13.33 ± 0.61 160.00 ± 8.66 98.95 ± 0.89 402 ± 3.7
D3b 14.16 ± 1.30 160.00± 10.00 99.43 ± 0.64 410 ± 3.4
D3c 17.43 ± 1.75 171.66 ± 10.27 97.97 ± 0.22 421 ± 3.6
D3d 13.95 ± 0.87 165.00 ± 5.77 97.99 ± 0.46 427 ± 4.1

Values as Mean ± SD (n=3)