Table 2.
Formulation | Weight (mg) | Thickness (µm) | Drug content (%) | Swelling index (%) |
---|---|---|---|---|
A1 | 10.33 ± 0.76 | 75 ± 5 | 100.63 ± 0.65 | 705 ± 11.4 |
A2 | 11.60 ± 0.37 | 85 ± 5 | 98.5 ± 0.54 | 598 ± 6.1 |
A3 | 12.36 ± 0.55 | 93 ± 5.77 | 101. 90 ± 0.80 | 412 ± 5.67 |
B1a | 20.96 ± 0.15 | 148. 33 ± 2.88 | 99.00 ± 0.59 | 750 ± 8.9 |
B1b | 21.36 ± 1.48 | 175.00 ± 8.02 | 98.75 ± 0.67 | 1110 ± 13.4 |
B1c | 11.93 ± 0.40 | 126. 00 ± 3.73 | 100.06 ± 0.70 | 1117 ±14.2 |
B2a | 18.93 ± 1.33 | 133.00 ± 5.77 | 98.12 ± 0.80 | 610 ± 7.9 |
B2b | 14.26 ± 1.10 | 116 ± 4.32 | 99.96 ± 0.49 | 1580 ± 16.8 |
C1a | 13.55 ± 0.25 | 100.00 ± 5.5 | 96.9 ± 0.96 | 799 ± 6.8 |
C1b | 14.23 ± 0.02 | 105.00 ± 8.66 | 98.63 ± 0.84 | 761 ± 5.9 |
C1c | 14.5 ± 1.85 | 113.00 ± 10.40 | 98.97 ± 0.99 | 520 ± 4.6 |
C1d | 16.76 ± 1.26 | 118.00 ± 7.63 | 102.10 ± 0.76 | 601 ± 5.1 |
C2a | 11.46 ± 1.10 | 95.50 ± 5.00 | 98.55 ± 0.27 | 608 ± 6.2 |
C2b | 16.52 ± 0.56 | 120.00 ± 0.01 | 99.99 ± 0.76 | 592 ± 6.9 |
C2c | 13.83 ± 0.20 | 113.30 ± 2.80 | 99.97 ± 0.89 | 589 ± 4.9 |
C3a | 10.20 ± 0.41 | 88.33 ± 5.77 | 98.43 ± 0.07 | 445 ± 5.5 |
C3b | 14.76 ± 0.65 | 115.00 ± 5.00 | 97.56 ± 0.55 | 454 ± 4.8 |
D1a | 10.00 ± 0.95 | 85.00 ± 10.00 | 98.50 ± 0.11 | 690 ± 7.9 |
D1b | 11.20 ± 1.05 | 91.66 ± 2.88 | 98.86 ± 0.49 | 601 ± 6.8 |
D1c | 12.46 ± 1.07 | 98.33 ± 7.63 | 99.80 ± 0.98 | 580 ± 5.8 |
D2a | 17.20 ± 0.84 | 115.00 ± 5.00 | 102.05 ± 0.87 | 501 ± 4.9 |
D2b | 17.76 ± 0.59 | 141.00 ± 4.18 | 99.12 ± 0.15 | 578 ± 5.1 |
D2c | 18.66 ± 1.15 | 150.00 ± 0.00 | 98.98 ± 0.23 | 703 ± 5.6 |
D3a | 13.33 ± 0.61 | 160.00 ± 8.66 | 98.95 ± 0.89 | 402 ± 3.7 |
D3b | 14.16 ± 1.30 | 160.00± 10.00 | 99.43 ± 0.64 | 410 ± 3.4 |
D3c | 17.43 ± 1.75 | 171.66 ± 10.27 | 97.97 ± 0.22 | 421 ± 3.6 |
D3d | 13.95 ± 0.87 | 165.00 ± 5.77 | 97.99 ± 0.46 | 427 ± 4.1 |
Values as Mean ± SD (n=3)