Table 5.
Pharmacokinetic parameters of doxorubicin after I.V. administration to rats (n=6).
| Dose, mg/Kg | 5.00 |
| AUC0-∞ (µg h mL -1) | 9.01 ± 1.91 |
| K el (h -1) | 0.09 ± 0.01 |
| t1/2 (h) | 7.88 ± 1.01 |
| MRT (h) | 5.92 ± 0.92 |
| Cl (mL Kg h -1) | 554.94 ± 10.74 |
| Vss (mL Kg -1) | 93.74 ± 8.32 |