Table 1.
| hpHC | HC | MCI | AD | p-value* | |
|---|---|---|---|---|---|
| n | 323 | 336 | 112 | 186 | |
| Age | 69.64 (6.38) | 70.73 (6.9) | 76.18 (7.69) | 78.8 (8.47) | p < 0.0001 |
| Gender (F/M) | 188/135 | 188/148 | 63/49 | 111/75 | p = 0.843 |
| APOEε4 (−ve/+ve) | 247/76 | 239/97 | 55/57 | 71/115 | p < 0.0001 |
| MMSE | 29 (1.12) | 29 (1.25) | 26 (2.6) | 20 (5.22) | p < 0.0001 |
| Composite score 1a | 0.24 (0.54) | −0.09 (0.57) | −1.31 (0.57) | −1.82 (0.56) | p < 0.0001 |
| Composite score 2b | 0.3 (0.67) | −0.15 (0.61) | −0.92 (0.79) | −1.85 (0.69) | p < 0.0001 |
a
Calculated as the average of the z score for California Verbal Learning Test Second Edition long delayed recall and Rey Complex Figure Test 30 minute delayed recall.
b
Calculated as the average of the z scores for Rey Complex Figure Test copy, Digit Symbol Coding, Boston Naming Test, Letter Fluency, Category Fluency, Digit Span (forwards), and Digit Span (backwards).
*
p-values calculated using χ2 test, and generalized linear model for the marginalized means.