Table 1.
Characteristics of sample and differences between statin exposed* vs unexposed.
| All | Statin exposed |
Statin unexposed |
P value | |
|---|---|---|---|---|
| Number | 295 | 109 | 186 | |
| Age (mean±SD), years | 80.1±2.8 | 79.8 | 80.3 | 0.300 |
| Women, N (%) | 168 (57%) | 55 (51%) | 113 (61%) | 0.089 |
| Black, N (%) | 118 (40%) | 75 (40%) | 43 (40%) | 0.902 |
| High school Education, N (%) | 256 (87%) | 97 (90%) | 159 (86%) | 0.367 |
| Hypertension, N (%) | 174 (60%) | 77 (71%) | 97 (52%) | 0.002 |
| Diabetes mellitus, N (%) | 48 (16%) | 25 (23%) | 23 (12%) | 0.022 |
| Coronary heart disease, N (%) | 64 (22%) | 37 (34%) | 27 (15%) | <0.001 |
| Stroke, N (%) | 23 (7%) | 9 (8%) | 14 (8%) | 0.825 |
| Alcohol consumption, N (%) | 172 (58%) | 66 (61%) | 106 (57%) | 0.624 |
| Peripheral arterial disease, N (%) | 10 (3%) | 7 (6%) | 3 (2%) | 0.042 |
| APOE4-positive status N (%) | 73 (26.1%) | 30 (28.0%) | 43 (24.9%) | 0.5557 |
| Serum LDL levels (mg/dl) | 115.1±31.7 | 96.0±24.8 | 125.9±30.2 | <0.0001 |
| 3MS | 92.77±6.17 | 93.1 | 92.3 | 0.30 |
*
Statin exposure defined as those identified as using a statin based on codes belonging to statin class of drugs.
3MS: Modified Mini-mental Status Examination
APOE4 positive stats: presence of apolipoprotein-epsilon 4 allele
LDL: low-density lipoprotein