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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Stat Methods Med Res. 2015 Jan 12;26(3):1078–1092. doi: 10.1177/0962280214567142

Figure 4.

Figure 4

Comparison of the variation of the standard RAR method for handling delayed primary outcomes and the S-P replacement algorithm on the NINDS rt-PA Stroke Study data (N = 160, simulations = 100). Primary outcome is the 90-day mRS, the surrogate outcome is the 24-hour NIHSS with a 1-year enrollment period.