. Author manuscript; available in PMC: 2016 Aug 1.

Published in final edited form as: Mult Scler. 2015 Jan 12;21(9):1139–1150. doi: 10.1177/1352458514558134

Table 1.

Demographic and Clinical Characteristics.

	HV (n= 15)	All MS (n = 34)	RRMS (n = 28)	SPMS/PPMS (n = 6)
Mean Age (sd)	41 (10)	43 (10)	42 (10)	46 (9)
% Female	67 %	53 %	57 %	33 %
Mean Years of Education (sd)	18 (3)	17 (2)	17 (2)	18 (3)
Mean Disease Duration in Years (sd)	n/a	10 (7)	9 (7)	13 (10)
% on MS Treatment	n/a	79 %	89 %	33 %^†
Median EDSS (Range)	n/a	3.0 (1–6.5)	2.5 (1–6)	5.5 (2–6.5)^†
Mean MSSS (sd)	n/a	4.6 (2.3)	4.27 (2.4)	6.1 (1.2)
Mean MSFC z-score (sd)	0.76 (0.40)	0.16 (0.50)^*	0.24 (0.40)	−0.29 (0.79)^†
9-Hole Peg Test z-score (sd)	1.3 (0.68)	0.01 (0.96)^*	0.16 (0.89)	−0.68 (1.1)
Timed 25 Foot Walk z-score (sd)	0.50 (0.41)	0.26 (0.44)^*	0.36 (0.24)	−0.17 (0.85)^†
PASAT z-score (sd)	0.51 (0.65)	0.18 (0.82)	0.22 (0.78)	−0.06 (1.1)

Demographic and clinical characteristics of the study cohort. HV = healthy volunteers. RRMS = relapsing remitting multiple sclerosis. SPMS = secondary progressive multiple sclerosis. PPMS = primary progressive multiple sclerosis. MSSS = Multiple Sclerosis Severity Score.

p < 0.05 for difference from healthy volunteers.

^†

p < 0.05 for difference from RRMS.