Table 2.
Serum biochemistry, after 4 weeks of binder treatment, at time of sacrifice.
| N | Weight g |
Creatinine μmol/L |
Ca mmol/L |
P mmol/L |
iPTH pg/mL |
AP mmol/L |
Ht % |
Ferritin ng/mL |
FGF23 ng/mL |
|
|---|---|---|---|---|---|---|---|---|---|---|
| CRF control | 18 | 313 ± 5 | 144 ± 11 | 2.32 ± 0.05 | 3.30 ± 0.29 | 3567 ± 593 | 430 ± 26 | 26.7 ± 0.5 | 2359 ± 281 | 0.7 (0.1–9.7) |
| CRF PA21 | 19 | 302 ± 4 | 141 ± 10 | 2.45 ± 0.03 | 2.06 ± 0.06a | 1459 ± 242a | 363 ± 19 | 26.4 ± 0.5 | 2185 ± 173 | 0.2 (0.1–7.6)a |
| CRF Se | 20 | 298 ± 4 | 147 ± 11 | 2.48 ± 0.03a | 2.51 ± 0.12a | 1569 ± 238a | 367 ± 19 | 21.9 ± 0.5a | 2188 ± 134 | 0.4 (0.1–10.6) |
| CRF La | 18 | 309 ± 4 | 140 ± 7.9 | 2.52 ± 0.03a | 2.24 ± 0.07a | 1360 ± 170a | 379 ± 29 | 22.7 ± 0.5a | 2361 ± 184 | 0.3 (0.1–9.1) |
Ca, calcium; Ht, hematocrit; iPTH, intact parathyroid hormone; La, lanthanum carbonate; AP, alkaline phosphatase; P, phosphorus; Se, sevelamer carbonate; PA21, sucroferric oxyhydroxide. a p < 0.05 versus CRF control. Values shown are mean ± SE except for FGF23 (median and range).