Table 1.
miRNAs involved in the regulation of arterial calcification.
| miRNAs | Observation | Ref. |
|---|---|---|
| miR-125b | Target SP7, inhibiting osteogenic transdifferentiation of VSMCs | [88, 89] |
|
| ||
| miR-133a | Target Runx2, inhibiting the osteogenic differentiation of VSMCs | [92] |
|
| ||
| miR-135a*/762/714/712* | Targets NCX1, PMCA1, and NCKX4, promoting VSMCs calcification | [94] |
|
| ||
| miR-204 | Target Runx2, inhibiting VSMCs calcification | [93] |
|
| ||
| miR-221/222 | Targets Enpp1 and Pit-1, contributing to arterial calcification | [95] |
|
| ||
| miR-223 | Targets Mef2c and RhoB, inducing VSMCs migration and calcification | [96] |
|
| ||
| miR-29a/b | Target ADAMTS-7, inhibiting VSMCs calcification | [90] |
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| ||
| miR-30b/30c | Target Runx2, inhibiting VSMCs calcification | [91] |