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. 2015 Mar 11;24(14):1658–1671. doi: 10.1089/scd.2014.0496

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Copyright 2015, Mary Ann Liebert, Inc.

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FIG. 1. — Enhanced mesenchymal stem cell (MSC) migration in response to sphingosine-1-phosphate (S1P) and LL37. Chemotaxis assays of human cord blood (hCB) or adipose-derived (hAD) MSCs exposed to the indicated concentrations of S1P (A) or LL-37 (B). The relative amount of migration is shown as the fold-change compared to the number of cells that transmigrated; mean±standard deviation (SD) from at least eight independent experiments are indicated; **P<0.01, compared to cells in the absence of S1P [one-way analysis of variance (ANOVA) with Bonferroni post-test]. Representative images for transwell insets from the migration assay are shown in the lower panel for the indicated MSCs. Control indicates medium alone.