Table 3. Cumulative effect of TNF/TRAF2/ASK1/p38 kinase signaling pathway variants on lung complications risk.

# of Risk Genotypes	Event, N(%)	No Event, N(%)	aOR(95%CI)	P-value
0 to 2	41(23.84%)	131(76.16%)	1(reference)
3	56(38.89%)	88(61.11%)	2.10(1.23–3.59)	6.46 × 10−8
4 to 5	97(48.50%)	103(51.50%)	3.95(2.40–6.50)	6.10 × 10−8
P for trend	1.63 × 10−8

^aAdjusted for age at surgery, gender, intra-operative transfusion, % DLCO predicted, and chest wall resection.