Scheme 1. Synthesis of Chrysosplenol C Analogues 5.
Reagents and conditions: (a) KOH,90% EtOH, reflux; (b) H2O2,10% NaOH, dioxane/ethanol (1:1) 5 °C–rt; (c) CH3I, NaH, DMF; (d) TFA/thioanisole at rt; (e) I2, DMSO, 1 h/100 °C.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.