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Crystal structures of compounds bound to DDR1 (PDB Codes: 5bvk, 5bvw, 5bvn and 5bvo). (a) Fragment 1 in DDR1 with pockets annotated. (b) Superimposition of the DDR1–dasatinib cocomplex and the DDR1–fragment 1 cocomplex. (c) Compound 4 superimposed on the crystallographic positioning of fragment 1. The four hydrogen bonding residues are marked. (d) Compound 9 in DDR1.
