Table 6. PK Properties of (R,S)-28 in Multiple Species.
| species | dose IV/PO (mpk) | CL (L/kg) | AUCNpo (μM h kg/mg) | t1/2 (h) | Fpo (%) |
|---|---|---|---|---|---|
| dog | 0.5/1 | 5.6 | 5.6 | 5.9 | 84 |
| rhesus | 1/2 | 25 | 0.51 | 7.2 | 30 |
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