FIG. 6.

Effects of Wnt-EGF signaling activity on the gene expression of the Shh-Wnt-EGF cascade components. RQ-PCR analysis of the (A) Shh, (B) Wnt, (C) EGF, and IGF1 genes, which were activated by the IC bladders that were injected with UCB-MSCs (see Fig. 4). Expression levels in the indicated bladder tissues are represented as % Gapdh (as determined using five or more independent experiments) and are shown as the mean±SEM (P<0.05, P<0.01 compared with IC group bladders, one-way ANOVA with Bonferroni post-test).