Table 3.
The areas of the component peaks in the deconvoluted FT-IR spectrum at the amide I' region of CLN025 as a percentage of the total area of the amide I' peak.
| Wavenumber / cm−1 | Buffer | TFE | MeOH | DMSO | Assignment |
|---|---|---|---|---|---|
| 1722 | 5 | Turn | |||
| 1712 | 5 | 24 | Turn or Asp | ||
| 1705 | 6 | 2 | Turn or Glu | ||
| 1696 | 2 | Turn | |||
| 1680 | 8 | Turn | |||
| 1675 | 5 | 5 | 25 | Turn or β-sheet | |
| 1658 | 27 | 53 | 57 | 45 | Random meander or loop |
| 1646 | 40 | 22 | Random meander | ||
| 1630 | 16 | 24 | 11 | 3* | β-sheet |
| 1612 | 4 | 4 | 3 | 3 | Pro |
*
May be due to the low frequency absorbance of turn structure rather than β-sheet.