TABLE 2.
Study | N | Outcome | Length of study | Controls | Predictors | Outcome | Est. ra |
---|---|---|---|---|---|---|---|
Allison et al., 2003 | 101 survivors of head and neck cancer |
Mortality | 1 year | Age, disease stage, cohabitation status |
High Optimism | OR = 1.12 (1.01, 1.24) | ror = −.22 |
Almada et al., 1991 | 1,871 members of the Western Electric Study |
All-cause mortality | 25 years | Age, blood pressure, smoking, cholesterol, alcohol consumption |
High Neuroticism High Cynicism |
RR = 1.20 (1.00, 1.40) RR = 1.4 (1.2, 1.7) |
rrr = .05 rrr = .09 |
Barefoot, Dahlstrom, & Williams, 1983 | 255 medical students | All-cause mortality | 25 years | High Hostility | p = .005 | re = .18 | |
Barefoot, Dodge, Peterson, Dahlstrom, & Williams, 1989 | 128 law Students | 29 years | Age | High Hostility | p = .012 | re = .22 | |
Barefoot, Larsen, von der Lieth, & Schroll, 1995 | 730 residents of Glostrup born in 1914 |
All-cause mortality | 27 years | Age, sex, blood pressure, smoking, triglycerid, FEV |
High Hostility | RR = 1.36 (1.06, 1.75) | rrr = .09 |
Barefoot et al., 1998 | 100 Older men and women | All-cause mortality | 14 years | Sex, age | High Trust | RR = 0.46 (0.24, 0.91) p < .03 |
rrr = −.23 re = −.22 |
Barefoot et al., 1987 | 500 members of the second Duke longitudinal study |
All-cause mortality | 15 years | Age, sex, cholesterol levels, smoking, physician ratings of health |
Suspiciousness | p = .02 | re = .10 |
Boyle et al., 2005 | 1,328 Duke University Medical Center patients |
All-cause mortality | 15 years | Sex, age, tobacco consumption, hypertension, hyperlipidemia, number of coronary arteries narrowed, left ventricular ejection fraction, artery bypass surgery |
High Hostility | HR = 1.25 (1.06, 1.47) p < .007 |
rhr = .07 re = .07 |
Boyle et al., 2004 | 936 Duke University Medical Center patients |
All-cause mortality | 15 years | Sex, age, tobacco consumption, hypertension, hyperlipidemia, number of coronary arteries narrowed, left ventricular ejection fraction, artery bypass surgery |
High Hostility | HR = 1.28 (1.06, 1.55) p <. 02 |
rhr = .08 re = .08 |
Christensen et al., 2002 | 174 chronic renal insufficiency patients |
Mortality | 4 years | Age, diabetic status, hemoglobin |
High Conscientiousness | HR = 0.94, B = −.066 (.03) p < .05 |
rB = −.17 re = −.15 |
High Neuroticism | HR = 1.05, B = .047 (.023) p <. 05 |
rhr = .15 re = .15 |
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Danner et al, 2001 | 180 nuns | Longevity | 63 years | Age, education, linguistic ability |
High Positive Emotion (sentences) High Positive Emotion (words) |
HR = 2.50 (1.20, 5.30) p < .01 HR = 3.20 (1.50, 6.80) p < .01 |
rhr = .18 re = .19 rhr = .22 re = .19 |
Different Positive Emotions | HR = 4.30 (1.70, 10.40) p < .01 |
rhr = .24 re = .19 |
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Denollet et al, 1996 | 303 CHD patients | Mortality | 8 years | CHD, age, social alienation, depression, use of benzodiazepines |
Type D personalityb | HR = 4.10 (1.90, 8.80) p = .0004 |
rhr = .21 re = .20 |
Everson et al., 1997 | 2,125 men from the Kuopio Eschemic Heart Disease Risk Factor Study |
All-cause mortality | 9 years | Age, SES | Cynical distrust | HR = 1.97 (1.26, 3.09) | rhr = .06 |
Friedman et al., 1993 | 1,178 members of the Terman Lifecycle Study |
Longevity | 71 years | Sex, IQ | High Conscientiousness | HR = .33, B = −1.11 (0.37) p < .01 |
rhr = .09 re = .08 |
High Cheerfulnessc | HR = 1.21, B = .19 (.07) p < .05 |
rhr = −.08 re = −.06 |
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Giltay, Geleijnse, Zitman, Hoekstra, & Schouten, 2004 | 397 men and 418 women of the Arnhem Elderly Study |
All-cause mortality | 9 years | Age, smoking, alcohol, education, activity level, SES, and marital status |
Dispositional optimism | Men’s HR = 0.58 (0.37, 0.91) p = .01 |
rhr = −.12 re = −.13 |
Women’s HR = 0.80 (0.51–1.25) p = .39 |
rhr = −.05 re = −.04 |
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Grossarth-Maticek, Bastianns, & Kanazir, 1985 | 1,335 inhabitants of Crvenka, Yugoslavia |
Mortality | 10 years | Age | High Rationalityd | p < .001 | re = .09 |
Hearn, Murray, & Luepker, 1989 | 1,313 University of Minnesota students |
All-cause mortality | 33 years | Age | High Hostility | p = .72 | re = .01 |
Hirokawa, Nagata, Takatsuka, & Shimizu, 2004 | 12,417 males and 14,133 females of the Takayama Study |
7 years | Age, smoking, marital status, BMI, exercise, alcohol, education, and number of children |
High Rationalityd | Men’s HR = 0.96 (0.83, 1.09) Women’s HR = 0.82, (0.70, 0.96) p < .05 |
rhr = −.01 rhr = −.02 re = −.02 |
|
Hollis, Connett, Stevens, & Greenlick, 1990 | 12,866 men from the Multiple Risk Factor Intervention Trial |
All-cause mortality | 6 years | Study group assignment, age, cigarettes, blood pressure, cholesterol |
High Type A personality | RR = 0.94 (0.89, 0.99) p < .01 |
rhr = −.02 re = −.02 |
Iribarren et al., 2005 | 5,115 members of the CARDIA study |
Non-AIDS, non- homicide-related mortality |
16 years | Age, sex, race | High Hostility | RR = 2.02 (1.07, 3.81) | rrr = .03 |
Kaplan et al, 1994 | 2,464 men from the Kuopio Eschemic Heart Disease Risk Factor Study |
All-cause mortality | 6 years | Age, income | Shyness | HR = 1.01 (0.63, 1.62) | rhr = .00 |
Korten et al., 1999 | 897 subjects aged 70 years and older |
Mortality | 4 years | Age, sex, general health, ADLs, illness, blood pressure, Symbol-Letter Modalities Test, MMSE |
High Neuroticism | HR = 0.53 (0.31, 0.90) | rhr = −.08 |
Kuskenvuo et al., 1988 | 3,750 Finnish male twins | All-cause mortality | 3 years | Age | High Hostility | RR = 2.98 (1.31, 6.77) | rrr = .04 |
Maruta, Colligan, Malinchoc, & Offard, 2000 | 839 patients from the Mayo Clinic |
All-cause mortality | 29 years | Sex, age, expected survival | Pessimism | HR = 1.20 (1.04, 1.38) p = .01 |
rhr = .09 re = .09 |
Maruta et al, 1993 | 620 from the Mayo Clinic | All-cause mortality | 20 years | Age, sex, hypertension, weight |
High Hostility | p = .069 | re = .07 |
McCarron, Gunnell, Harrison, Okasha, & Davey-Smith, 2003 | 8,385 former male students | All-cause mortality | 41 years 25 years | Smoking, father’s SES, BMI, maternal and paternal vital status |
Mental instability | RR = 2.05 (1.36–3.09) p < .01 |
rrr = .04 re = .03 |
McCranie, Watkins, Brandsma, & Sisson, 1986 | 478 physicians | All-cause mortality | 25 years | High Hostility | p = .789 | re = −.01 | |
Murberg, Bru, & Aarsland, 2001 | 119 heart failure patients | Mortality | 2 years | Age, sex, disease severity | Neuroticism | HR = 1.140 (1.027, 1.265) p = .01 |
rhr = .23 re = .24 |
Osler et al, 2003 | 7,308 members of Project Metropolit in Copenhagen, Denmark |
All-cause mortality | 49 years | IQ, birth weight, SES | Creativity | HR = 1.17 (0.89, 1.54) | rhr = .01 |
C. Peterson, Seligman, Yurko, Martin, & Friedman, 1998 | 1,179 members of the Terman Lifecycle Study |
Mortality | 51 Years | Global pessimism | OR = 1.26, p < .01 | re = .08 | |
Schulz et al., 1996 | 238 cancer patients | Cancer mortality | 8 months | Site of cancer, physical symptoms, age |
Pessimism | OR = 1.07, B = .07 (.05) |
rB = .08 |
Pessimism × Age interaction |
OR = 0.88, B = −.12 (.06), p < .05 |
rB = −11 re = .13 |
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Surtees, Wainwright, Luben, Day, & Khaw, 2005 | 20,550 members of the EPIC-Norfolk study (8,950 men and 11,600 women) |
Mortality | 6 years | Age, disease, cigarette smoking history |
Hostility | Men’s RR = 1.06 (0.99, 1.14) Women’s RR = 1.00 (.91, 1.09) |
rrr = .02 rrr = .00 |
Surtees, Wainwright, Luben, Khaw, & Day, 2003 | 18,248 members of the EPIC-Norfolk study |
Mortality | 6 years | Age, disease, social class, cigarette smoking history |
Strong sense of coherence | RR = 0.76 (0.65, 0.87) p < .0001 (taken from abstract) |
rhr = −.03 re = −.03 |
Weiss & Costa, 2005e | 1,076 members of the Medicare Primary and Consumer-Directed Care Demonstration |
All-cause mortality | 5 years | Gender, age, education, diabetic status, cardiovascular disease, functional limitations, self- rated health, cigarette smoking, depression, Neuroticism, Agreeableness |
Conscientiousness | HR = 0.51 (0.31, 0.85) p < .05 |
rhr = −.08 re = −.06 |
Gender, age, education diabetic status, cardiovascular disease, functional limitations, self- rated health, cigarette smoking, depression, Conscientiousness, Agreeableness |
Neuroticism | HR = 0.99 (0.97, 1.00) p < .05 |
rhr = −.04 re = −.06 |
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Gender, age, education, diabetic status, cardiovascular disease, functional limitations, self- rated health, cigarette smoking, depression, Neuroticism, Conscientiousness |
Agreeableness | HR = 0.99 (0.98, 1.00) | rhr = −.06 | ||||
Wilson et al., 2003 | 851 members of the Religious Orders Study |
All-cause mortality | 5 years | Age, sex, education, health | Trait anxiety | RR = 1.04 (0.99, 1.09) p = .01 (unadjusted) |
rrr = .05 re = .09 |
Trait anger | RR = 1.03 (0.95, 1.12) p = .64 (unadjusted) |
rrr= .02 re = .02 |
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Wilson et al., 2005 | 6,158 members (aged 65 years and older) of the Chicago Health and Aging Project |
All-cause mortality | 6 years | Age, sex, race, education | Neuroticism Extraversion |
RR = 1.016 (1.010, 1.020) RR = 0.984 (0.978, 0.991) |
rrr= .07 rrr = −.05 |
Wilson et al., 2004 | 883 members of the Religious Orders Study |
All-cause mortality | 5 years | Age, gender, education, remaining personality traits |
Neuroticism | RR = 1.04 (1.02, 1.08) p < .02 (unadjusted) |
rrr= .12 re = .09 |
Extraversion | RR = 0.96 (0.94, 0.99) p < .001 (unadjusted) |
rrr= −.08 re = −.11 |
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Openness | RR = 1.005 (0.970, 1.040) p = .014 |
rrr= .01 re = .08 |
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Agreeableness | RR = 0.964 (0.930, 1.000) p = .011 |
rrr= −.06 re = −.09 |
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Conscientiousness | RR = 0.968 (0.94, 0.99) p < .001 |
rrr= −.07 re = −.11 |
Note. Confidence intervals are given in parentheses. HR = hazard ratio; RR = relative risk ratio; OR = odds ratio; rrr = correlation estimated from the rate ratio; rhr = correlation estimated from the hazard ratio; ror = correlation estimated from the odds ratio; rB = correlation estimated from a beta weight and standard error; re = requivalent (correlation estimated from the reported p value and sample size); FEV = forced expiratory volume; CHD = coronary heart disease; SES =socioeconomic status; BMI =body-ass index; ADLs =activities of daily living; MMSE =Mini Mental State Examination.
The direction of the correlation was derived by choosing a positive pole for each dimension (high Extraversion, Agreeableness, Conscientiousness, Neuroticism, and Openness) and assuming that each dimension, with the exception of Neuroticism, would be negatively related to mortality in its positive manifestation.
Type D personality was categorized as a Neuroticism measure as it correlates more consistently with high Neuroticism (De Fruyt & Denollet, 2002), though it should be noted that it has strong correlations with low Extraversion, low Agreeableness, and low Conscientiousness.
On the basis of the correlations presented in Martin and Friedman (2000), cheerfulness was categorized as a measure of Agreeableness.
Rationality was not categorized into the Big Five because it measures suppression of aggression, which does not easily fall into one of the five broad domains.
The discrepancy in the Hazard ratios results from the fact that the Neuroticism scores were continuous and the Conscientiousness scores were trichotomized.