Table 2. Comprehensive selection of published studies with at least 30 patients treated with interstitial therapy and their success and complication rates, based on an extensive search of the PubMed database.
| Author | Year | Patients (n) | Tumor size (cm) | Method | Primary success rate (%) | Follow-up (mDonths) | Freedom of recurrence (%) | Severe complication (%) | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 year | 3 years | 5 years | ||||||||
| Mayo-Smith (e10) | 2003 | 32 | 1–5 | RFA | 81 | 3–36 | 100 | 96 | 0 | |
| Varkarakis (27) | 2005 | 49 | 1–4 | RFA | 87 | 12–48 | 100 | 1.8 | ||
| Gervais (e11) | 2005 | 100 | 1.1–8.9 | RFA | 90 | 3–72 | 100 | 98 | 4 | |
| Levinson (e12) | 2008 | 31 | 1–4 | RFA | 97 | 41–80 | 97 | 94 | 90 | |
| Ferakis (30) | 2010 | 31 | 1.3–7.5 | RFA | 90 | 36–84 | 97 | 90 | 88 | |
| Tracy (32) | 2010 | 208 | 1–5.4 | RFA | 98 | 36–90 | 98 | 97 | 93 | |
| Zagoria (31) | 2011 | 41 | 0.7–8.2 | RFA | 88 | 36–68 | 88 | 83 | 66 | 0 |
| Ji (e13) | 2011 | 106 | 0.9–5.5 | RFA | 99 | 12–48 | 98 | 98 | 0 | |
| Karam (e14) | 2013 | 150 | 0.9–7.1 | RFA | 100 | 6–95 | 100 | 96 | ||
| Atwell (38) | 2013 | 222 | 1–3 | RFA | 98 | 6–102 | 100 | 97 | 93 | 4 |
| Bandi (e15) | 2007 | 78 | Ø 2.6 | CA | 95 | 3–60 | 100 | 98 | 8 | |
| Georgiades (36) | 2008 | 46 | 1–7 | CA | 100 | 4–81 | 97 | 8 | ||
| Spreafico (e16) | 2011 | 36 | 1.2–7 | CA | 96 | 1–36 | 96 | 96 | 6 | |
| Guazzoni (e17) | 2010 | 123 | 0.5–4 | CA | 98 | 12–96 | 100 | 98 | 5 | |
| Rodriguez (24) | 2011 | 117 | 1–7 | CA | 100 | 7–172 | 98 | 92 | 7 | |
| Pirasteh (37) | 2011 | 70 | 1–7 | CA | 99 | 6–60 | 98 | 93 | ||
| Guillotreau (e18) | 2012 | 226 | Ø 2.2 | CA | 100 | 8–66 | 95 | 89 | 3 | |
| Duffey (e19) | 2012 | 116 | 1.1–5.5 | CA | 94 | 1–112 | 91 | 91 | 85 | 2 |
| Atwell (38) | 2013 | 163 | 0.9–3 | CA | 98 | 6–78 | 97 | 95 | 95 | 5 |
CA, cryoablation; RFA, radiofrequency ablation