Table 2.
Cluster | MNI Coordinates | ||||
---|---|---|---|---|---|
Location of peak activation | Size | t(34) | x | y | z |
Participants with Autism | |||||
Bilateral lingual, inferior occipital, fusiform, calcarine, and cerebellum; left middle occipital and superior occipital; right inferior temporal |
4285 | 9.34 | −24 | −96 | 10 |
R superior occipital, middle occipital, and inferior parietal |
990 | 7.88 | 30 | −74 | 24 |
R postcentral and inferior parietal | 24 | 4.79 | 56 | −24 | 52 |
R inferior parietal | 85 | 3.81 | 42 | −38 | 40 |
L inferior parietal | 340 | 6.32 | −38 | −40 | 38 |
L inferior parietal | 17 | 3.37 | −58 | −30 | 46 |
Bilateral superior medial frontal, middle cingulate, and supplementary motor |
277 | 5.82 | 6 | 28 | 40 |
R middle frontal, inferior frontal, and precentral |
753 | 4.82 | 56 | 22 | 38 |
R middle frontal and inferior frontal | 104 | 4.17 | 48 | 44 | 26 |
R middle frontal and superior frontal | 74 | 3.85 | 28 | 6 | 60 |
R insula and inferior orbital frontal | 289 | 6.77 | 34 | 22 | 2 |
L middle frontal, inferior frontal, and precentral |
135 | 4.02 | −48 | 10 | 32 |
L middle frontal and superior frontal | 28 | 3.87 | −24 | 0 | 52 |
L inferior frontal | 41 | 3.45 | −58 | 14 | 10 |
L insula and inferior frontal | 40 | 3.83 | −34 | 24 | 2 |
R thalamus, hippocampus, and lingual | 139 | 5.02 | 24 | −24 | −8 |
R thalamus | 29 | 3.92 | 10 | −14 | 10 |
L thalamus, hippocampus, and lingual | 111 | 5.75 | −20 | −28 | −2 |
L thalamus | 7 | 3.31 | −12 | −20 | 10 |
Normal Control Participants | |||||
Bilateral lingual, inferior occipital, middle occipital, superior occipital, fusiform, calcarine, cerebellum, and inferior parietal |
11206 | 12.65 | −28 | −74 | 30 |
Bilateral precuneus | 10 | 3.61 | 2 | −64 | 44 |
Bilateral cuneus | 16 | 3.28 | 4 | −86 | 32 |
Bilateral superior medial frontal, middle cingulate and supplementary motor area |
561 | 6.31 | 0 | 14 | 52 |
R middle frontal, inferior frontal, and precentral |
2146 | 6.98 | 26 | 2 | 52 |
R insula and inferior frontal | 87 | 4.01 | 32 | 26 | −2 |
L middle frontal, inferior frontal, and precentral |
925 | 8.86 | −42 | 42 | 32 |
L middle frontal, superior frontal, and precentral |
206 | 5.52 | −24 | −2 | 54 |
L middle frontal and superior frontal | 21 | 4.28 | −32 | 64 | 8 |
L insula and inferior frontal | 84 | 4.24 | −32 | 28 | 0 |
Bilateral cerebellum and right lingual | 13 | 3.21 | 6 | −42 | 0 |
R thalamus | 44 | 4.51 | 20 | −28 | 10 |
L thalamus | 47 | 4.37 | −20 | −30 | 8 |
Notes: The threshold for significant activation was p < .005 for a spatial extent of at least 6 voxels, uncorrected for multiple comparisons. Region labels apply to the entire extent of the cluster.
t-values and MNI coordinates are for the peak activated voxel in each cluster only.