Table 3.
Areas of activation for each group for the contrast between the working memory tasks (collapsed across three conditions) with the Fixation baseline
Location of peak activation | Brodmann’s area |
Cluster size |
t(10) | MNI coordinates |
||
---|---|---|---|---|---|---|
x | y | z | ||||
Autism | ||||||
L inferior frontal | 46 | 40 | 4.06 | −50 | 22 | 26 |
R precentral | 9 | 2201 | 5.98 | 42 | 8 | 36 |
R supplementary motor area | 6 | 64 | 4.63 | 4 | 8 | 62 |
R middle cingulate | 32 | 208 | 6.52 | 6 | 22 | 44 |
L inferior parietal | 40 | 581 | 6.39 | −38 | −54 | 50 |
R inferior parietal | 40 | 1169 | 6.65 | 52 | −44 | 44 |
R fusiform/R inferior temporal | 20 | 45 | 4.70 | 52 | −50 | −16 |
L fusiform | 37 | 53 | 4.35 | −36 | −54 | −28 |
L cerebellum | 19 | 136 | 4.87 | −34 | −70 | −28 |
Control | ||||||
L middle frontal | 10 | 709 | 7.63 | −34 | 54 | 14 |
L middle frontal | 6 | 189 | 6.71 | −32 | 2 | 58 |
R orbital frontal | 47 | 2281 | 8.57 | 38 | 24 | −12 |
L supplementary motor area | 8 | 1717 | 8.08 | −2 | 20 | 50 |
L supplementary motor area | 6 | 41 | 4.30 | −8 | −6 | 62 |
L precentral | 9 | 3942 | 13.44 | −36 | 4 | 30 |
R middle cingulate | 33 | 395 | 7.08 | 6 | 10 | 26 |
L inferior parietal | 7, 40 | 735 | 9.34 | −32 | −58 | 42 |
R angular gyrus | 7, 39 | 1585 | 8.80 | 36 | −64 | 42 |
R middle temporal | 22 | 60 | 6.91 | 58 | −44 | 8 |
L fusiform | 37 | 34 | 6.45 | −44 | −62 | −24 |
R fusiform | 37 | 115 | 4.85 | 42 | −50 | −26 |
L inferior occipital | 18 | 52 | 6.37 | −34 | −88 | −6 |
L putamen, L amygdala | 34 | 50 | 5.52 | −24 | 6 | −14 |
R thalamus | 44 | 3.86 | 20 | −12 | 8 |
Note: L = left, R = right. The threshold used for significant activation was P < 0.005 for a spatial extent of at least 10 voxels, uncorrected for multiple comparisons. Region labels apply to the entire extent of the cluster. The t-values and MNI coordinates are for the peak activated voxel in each cluster only.