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Phenotypic analysis of IFN-γ–secreting cells. Examples of (A) a CD4+ Integrase-specific IFN-γ response and (B) a CD8+ Vif-specific IFN-γ response and (C and D, respectively) corresponding memory phenotyping. E and F summarize the memory phenotype of IFN-γ–secreting cells for all phenotypically characterized CD4+ and CD8+ responses, respectively. CM, central memory (CD45RA−CCR7+); EM, effector memory (CD45RA−CCR7−); TEMRA, terminally differentiated effector memory (CD45RA+CCR7−).
