Table S2.
Antibodies, sources, applications, and dilutions used in this article
| Target and antibody (clone) | Epitope/immunogen | Application/dilution | Source; catalog |
| α-Tubulin | |||
| Mouse monoclonal (TU-02) | a.a. 1–451 of procine α-Tubulin | WB/1:1,200 | Santa Cruz; sc-8035 |
| ADAM10 | |||
| Rabbit polyclonal | CT a.a. 732–745 of human ADAM10 | WB/1:1,000 | Millipore; AB19026 |
| Mouse monoclonal | NT a.a. 1–300 of human ADAM10 | ICC/1:500 | Santa Cruz, sc-28358 |
| ADAM17 | |||
| Rabbit polyclonal | CT a.a. 807–823 of human ADAM10 | WB/1:1,100 | Abcam; ab2051 |
| APP | |||
| Mouse monoclonal (22C11) | NT a.a. 66–81 of pre-A4 | ICC/1:700 | Millipore; MAB348 |
| WB/1:1,000 | |||
| IP/1:150 | |||
| Goat polyclonal | NT a.a. 44–63 of APP | ICC/1:500 | Millipore; AB1593 |
| Rabbit polyclonal (Poly8134) | β-secretase-cleaved neoepitope | WB/1:500 | BioLegend; 813401 |
| Mouse monoclonal (C1/6.1) | CT a.a. 676–695 of APP | WB/1:1,000 | BioLegend; 802802 |
| β-Actin | |||
| Mouse monoclonal (AC-15) | a.a. 1–15 of Xenopus laevis β-actin | WB/1:5,000 | Abcam; ab6276 |
| β-Amyloid | |||
| Mouse monoclonal (M3.2) | a.a. 10–15 of murine Aβ | WB/1:800 | BioLegend; 805701 |
| IP/1:300 | |||
| Rabbit polyclonal (A11) | Oligomer specific | WB/1:600 | Millipore; AB9234 |
| Mouse monoclonal (6E10) | a.a. 1–16 of human Aβ | IHC/1:300 | BioLegend; 803015 |
| IP/1:400 | |||
| WB/1:1,200 | |||
| Rabbit monoclonal (D54D2) | NT of human Aβ | WB/1:1,000 | Cell Signaling; 8243 |
| β-Tubulin | |||
| Rabbit polyclonal (H-235) | a.a. 210–444 of human β-Tubulin | WB/1:1,200 | Santa Cruz; sc-9104 |
| BACE1 | |||
| Rabbit monoclonal (EPR3965) | Synth peptide to human BACE1 | WB/1:1,000 | Epitomics; 2882–1 |
| CBP | |||
| Rabbit polyclonal (A-22) | NT of human CBP | ChIP/1:150 | Santa Cruz; sc-369x |
| GAPDH | |||
| Mouse monoclonal (6C5) | Synth peptide against rabbit GAPDH | WB/1:2,000 | Santa Cruz; sc-32233 |
| GFAP | |||
| Rabbit polyclonal | Synth peptide to cow GFAP | WB/1:1,500 | Dako; z0334 |
| GFP | |||
| Goat polyclonal | FL Aequorea victoria sequence | WB/1:1,000 | Rockland; 600–101-215 |
| ICC/1:500 | |||
| Histone H3 | |||
| Goat polyclonal (C-16) | CT of human H3 | WB/1:400 | Santa Cruz; sc-8654 |
| Iba1 | |||
| Goat polyclonal | CT a.a. 135–147 of human Iba-1 | WB/1:900 | Abcam; ab5076 |
| MAP-2 | |||
| Rabbit polyclonal | Purified rat MAP-2 | ICC/1:700 | Millipore; AB5622 |
| NcoR1 | |||
| Rabbit polyclonal | a.a. 2427–2443 of mouse NcoR1 | ChIP/1:300 | Abcam; ab3482 |
| NeuN | |||
| Mouse monoclonal (A60) | Purified mouse brain nuclei | WB/1:1,000 | Millipore; MAB377 |
| p300 | |||
| Mouse monoclonal (NM11) | a.a. 2071–2091 | ChIP/1:150 | Abcam; ab3164 |
| PGC1α | |||
| Rabbit polyclonal (H-300) | NT a.a. 1–300 of human PGC1α | ChIP/1:150 | Santa Cruz; sc-13067 |
| PPARα | |||
| Rabbit polyclonal | NT of mouse PPARα | WB/1:600 | Rockland; 600–401-421 |
| Mouse monoclonal (3B6) | Recombinant FL protein | ChIP/1:200 | Abcam; ab2779 |
| PPARβ | |||
| Rabbit polyclonal (H-74) | a.a. 2–75 of human PPARβ | WB/1:300 | Santa Cruz; sc-7197 |
| PPARγ | |||
| Mouse monoclonal (E-8) | a.a. 480–505 of human PPARγ | WB/1:300 | Santa Cruz; sc-7273 |
| Presenilin-1 | |||
| Rabbit polyclonal | CT a.a. 275–367 of human PSEN1 | WB/1:1,000 | Millipore; AB5308 |
| Rabbit polyclonal | NT of Human PSEN1 (Bleed #13) | WB/1:4,000 | Gift of Robert Vassar |
| RNA Pol II | |||
| Mouse monoclonal (CTD4H8) | CT (YSPT[pS]PS) of hu. RNA Pol II | ChIP/1:200 | Millipore; 05–623 |
| RXRα | |||
| Rabbit polyclonal (d-20) | Synth peptide to NT of hu. RXRα | ChIP/1:200 | Santa Cruz; sc-553x |
ICC, immunocytochemistry; IHC, immunohistochemistry; WB, Western blot.