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. 2015 Jun 8;112(27):8278–8283. doi: 10.1073/pnas.1506761112

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Fig. 6. — Growth inhibitory activity for LNM E1 (2) against normal (HPEC) and cancer (DU-145 and LNCaP) cells treated with selected agents modulating ROS levels and compared with LNM (1) as a control. DNA levels were measured as an indicator of cell growth, and all data were normalized to growth effect with vehicle as controls. (A) Effects of 1 (●) and 2 (▼) on normal HPEC. (B) Effects of 1 on DU-145 (●) or LNCaP (○) cells. (C) Effects of 2 on DU-145 cells (●) or DU-145 cells treated with BE-3-3-3 (red filled square) or BE-3–3-3 and MDL 72527 (blue triangle). (D) Effects of 2 on LNCaP cells (●) or LNCaP cells treated with R1881 (red filled square) or R1881 and vitamin E (blue triangle). (E) Effects of 2 on LNCaP cells (●) or LNCaP cells treated with BE-3-3-3 (red filled square) or BE-3-3-3 and MDL 72527 (blue triangle).