MCTs and cytochrome c oxidase expression in solid tumours
A, expression of the monocarboxylate transporters (MCTs), lactate dehydrogenase (LDH) isoforms and CD147 in the solid tumour of one mouse from each group detected by immunoblotting. The expression of MCT1 and MCT4 was normalized to an MCT1 signal generated by 5 μg of mouse erythrocyte ghost expression. CD147, LDH-A AND LDH-B expression were normalized to the expression of β-actin in solid tumours. B, cytochrome c oxidase (COX) subunit IV expression (normalized to the expression of β-actin) in solid tumours at the end of the study; Control n = 9, Trained n = 9, Control + XCT790 n = 9, Trained + XCT790 n = 9. Values are the means ± SD. *Significant difference between the groups (P < 0.01).