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. 2015 Apr 24;172(13):3313–3325. doi: 10.1111/bph.13126

Figure 5.

Figure 5

Contribution of IFN-γ to the effects of α-GalCer. Liquid bone marrow cultures were established from C57BL/6 wild-type controls and from IFN-γ-deficient mutants (IFN-γ-KO) (panel A), or from BALB/c mice (panels B and C), in the presence of IL-5 alone, or together with α-GalCer (+αGC), at the indicated concentrations. Where indicated, cultures also received: panel (B) (+IFN-γ): rmIFN-γ at the indicated concentrations or medium (−) as a control; panel (C): monoclonal neutralizing antibodies to an irrelevant antigen (isotype control) or to mIFN-γ. Data are mean ± SEM of the numbers of EPO+ recovered from cultures at day 7. *P ≤ 0.01, significantly different as indicated; n = 4 (panel A); n = 3 (panels B and C).