Figure 1.

Effects of single TA₁ injection on heart rate and body temperature. (A) Body temperature and (B) heart rate were measured using radiotelemetry before and during 6 h post injection (X) in TA₁-injected (50 mg·kg⁻¹) compared with sham-injected animals. Data are presented as mean ± SEM of 8–12 male mice for each group. The area under the curve was calculated for the first hour post injection, including a positive control using 3-T₁AM (50 mg·kg⁻¹, grey bars). *P < 0.05 (Student's t-test)