Table 3. PAFE results for C. parapsilosis complex.
Isolate | Micafungin (μg/ml) | Killing (log) | PAFE/TK 1 | PAFE (h) | |
---|---|---|---|---|---|
TK | PAFE | ||||
C. parapsilosis ATCC 22019 | 0.25 | NA 2 | NA | 0 | |
2 | NA | NA | 0 | ||
8 | 1.67 | 0.08 | 2.56 | 6 | |
C. parapsilosis ATCC 90018 | 0.25 | 0.16 | NA | 0 | |
2 | 0.12 | NA | 0 | ||
8 | 2.12 | 0.07 | 0.89 | 5.3 | |
C. parapsilosis UPV/EHU 09–378 | 0.25 | NA | NA | 0 | |
2 | 0.07 | 0.31 | 100 | 0 | |
8 | 5.27 | 0.22 | 0 | 15.7 | |
C. metapsilosis ATCC 96143 | 0.25 | 0.02 | NA | 0 | |
2 | NA | NA | 0 | ||
8 | 5.42 | NA | 5.4 | ||
C. metapsilosis UPV/EHU 07–045 | 0.25 | NA | 0.03 | 0 | |
2 | NA | NA | 0 | ||
8 | 5.24 | 0.11 | 0 | 9.3 | |
C. orthopsilosis ATCC 96139 | 0.25 | NA | NA | 2 | |
2 | NA | NA | 2 | ||
8 | 5.43 | NA | 11 | ||
C. orthopsilosis UPV/EHU 07–035 | 0.25 | NA | NA | 0 | |
2 | NA | NA | 0 | ||
8 | 1.91 | NA | 3.8 |
1 Ratio of the log killing during PAFE experiments to the log killing during TK experiments.
2 NA, not applicable (without any reduction in colony counts compared with the starting inoculum).