Table 8. Change of N₂MBW results after reanalysis with different signal delay times.

Settings	LCI	FRC	Scond	Scond*VT	Sacin	Sacin*VT
Individual signal changes
O2 delay -20ms	↑↑	↓↓	↔	↔	↑↑	↑↑
O2 delay -40ms	↑↑	↓↓	↔	↔	↑	↑↑
O2 delay -60ms	↑↑	↓↓	↔	↔	↑↑	↑↑
O2 delay +20ms	↓↓	↑↑	↔	↔	↓	↓
O2 delay +40ms	↓↓	↑↑	(↓)	(↓)	↓↓	↓↓
O2 delay +60ms	↓↓	↑↑	↓	↓	↓↓	↓↓
CO2 delay -10ms	↓↓	↑↑	(↓)	(↓)	↔	↔
CO2 delay +10ms	↑↑	↓↓	↑	↑	↔	↔
Simultaneous signal changes using different delays
O2 -100ms and CO2 -10ms	↑↑	↓↓	↔	↔	↑↑	↑↑
O2 +100ms and CO2 +10ms	↓↓	↑↑	↓	↓	↓↓	↓↓
O2 -100ms and CO2 +10ms	↑↑	↓↓	↔	↔	↑↑	↑↑
O2 +100ms and CO2 -10ms	↓↓	↑↑	↓↓	↓↓	↓↓	↓↓
Simultaneous signal changes using similar delays
O2 -40ms and CO2 -40ms	↑↑	↓↓	↔	↔	↑	↑↑
O2 +40ms and CO2 +40ms	↓↓	↑↑	↔	↔	↓↓	↓↓
O2 +80ms and CO2 +80ms	↓↓	↑↑	↔	↔	↓↓	↓↓

Change of N₂MBW test results of 30 children after simulation with changed signal delay times. Results of standard N₂MBW test were compared to the test with changed setting parameter by Wilcoxon signed-rank test and marked as follows: ↓↓ difference of p < 0.001, ↓ p < 0.01, (↓) p < 0.05, ↔ no significant change. Of note, for simultaneous signal changes using similar time steps, delays between O₂ and CO₂ sensor were kept constant.