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. 2015 Jul 13;10(7):e0132515. doi: 10.1371/journal.pone.0132515

Table 8. The cut-off value for the L/N ratio based on ROC analysis.

Subject All lesions Glioma Metastasis
SUV L/N ratio* AUC L/N ratio* AUC L/N ratio* AUC
Around Max 1.4 0.72 1.5 0.63 1.4 0.79
Mean 1.3 0.70 1.3 0.61 1.3 0.76
Max mean 1.7 0.68 1.8 0.69 1.6 0.71
Contralateral Max 1.3 0.79 1.4 0.68 1.3 0.89
Mean 1.3 0.77 1.4 0.66 1.3 0.85
Max mean 1.7 0.68 1.8 0.59 1.6 0.66
Frontal lobe Max 1.5 0.72 1.2 0.60 1.5 0.81
Mean 1.4 0.78 1.2 0.60 1.4 0.88
Max mean 1.6 0.74 1.4 0.63 1.6 0.84
Cerebellum Max 1.2 0.79 1.0 0.60 1.2 0.86
Mean 1.1 0.81 1.2 0.71 1.1 0.89
Max mean 1.4 0.75 1.2 0.59 1.3 0.83

Results for the four reference regions, three types of L/N, and two types of patient as well as for all patients. L/N ratio: lesion to normal tissue ratio, SUV: standardized uptake value, Max: SUVmax (lesion) / SUVmax (reference), Mean: SUVmean (lesion)/ SUV mean (reference), L/N max mean: SUVmax (lesion)/ SUV mean (reference), AUC: area under the receiver-operating characteristic curve.

*The number shown in L/N ratio is cut off value based on ROC analysis.