Table 2. In Vitro Cytotoxicity Results for Representative Compoundsa.
compd | IC50 (μM, Jurkat cell) | compd | IC50 (μM, Jurkat cell) |
---|---|---|---|
5 | >100 | 27 | 16.8 |
8 | >100 | 28 | >100 |
9 | 7.59 | 29 | 17.6 |
15 | 48.2 | 30 | >100 |
17 | 79.9 | 31 | >100 |
18 | >100 | 33 | 52.4 |
The experimental procedure for the in vitro cytotoxicity assay was described previously.11