Table 7.
Microarray analysis of adhesion molecule–related gene expression regulation upon FH535 treatment
| Gene | ID | Normalized intensity
|
|
|---|---|---|---|
| Control | FH535 | ||
| CD44 | 960 | 15.006962 | 16.199093 |
| ITGB5 | 3693 | 13.888797 | 13.484464 |
| LAMC1 | 3915 | 13.492421 | 14.51922 |
| LAMB1 | 3912 | 12.817556 | 13.73472 |
| ITGA3 | 3675 | 12.797894 | 12.391577 |
| ITGB1 | 3688 | 12.738785 | 13.636554 |
| ITGAV | 3685 | 12.278682 | 14.3424 |
| ITGA6 | 3655 | 12.273888 | 14.392418 |
| ITGA5 | 3678 | 12.169847 | 10.866323 |
| SGCE | 8910 | 12.047686 | 12.282321 |
| ICAM1 | 3383 | 12.0056095 | 11.118488 |
| ITGB4 | 3691 | 11.982763 | 11.56935 |
| CTNNB1 | 1499 | 11.900537 | 11.841962 |
| CTNNA1 | 1495 | 11.841962 | 11.517105 |
| COL16A1 | 1307 | 11.647751 | 10.777789 |
| COL5A1 | 1289 | 11.607744 | 10.272581 |
| COL6A1 | 1291 | 11.396863 | 10.174638 |
| CTGF | 1490 | 10.809845 | 11.98555 |
| CTNND1 | 1500 | 10.622252 | 11.350482 |
| THBS3 | 7059 | 10.1687765 | 9.736564 |
| ITGAM | 3684 | 10.003317 | 8.889115 |
| THBS1 | 7057 | 9.663341 | 9.193558 |
| ITGA7 | 3679 | 9.627002 | 8.878363 |
| MMP15 | 4324 | 9.533566 | 8.395943 |
| COL7A1 | 1294 | 8.711706 | 7.6560946 |
| LAMB3 | 3914 | 8.550647 | 8.319239 |
| HAS1 | 3036 | 8.124433 | 7.6573296 |
| ADAMTS13 | 11093 | 8.074093 | 8.375932 |
| SPG7 | 6687 | 7.990712 | 6.850328 |
| COL12A1 | 1303 | 7.404812 | 8.422412 |
| CDH1 | 999 | 7.3595057 | 7.319695 |
| COL14A1 | 7373 | 7.3424816 | 6.805993 |
| TNC | 3371 | 7.329479 | 6.564947 |
| VCAN | 1462 | 7.045421 | 6.763195 |
| VTN | 7448 | 6.8925853 | 6.3992944 |
| CLEC3B | 7123 | 6.6491346 | 6.5587797 |
| ITGB2 | 3689 | 6.6435785 | 7.713477 |
| ITGA2 | 3673 | 6.538141 | 10.171594 |
| SPP1 | 6696 | 6.37645 | 6.842924 |
| LAMA3 | 3909 | 6.1783895 | 5.889333 |
| SELE | 6401 | 5.8820415 | 7.629673 |
| CTNND2 | 1501 | 5.4170265 | 5.9111185 |
| ITGA1 | 3672 | 5.3547735 | 7.6031985 |