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Representative ex vivo antigen-specific responses of KIR3DS1+CD8+ T cells. Gating was on CD3+KIR3DS1+ cells as in (a) with CD8+ cells producing IFN-γ shown in the upper right hand quadrants of the subsequent plots. Freshly-isolated PBMC from a KIR3DS1 homozygous individual were unstimulated (b) or incubated with overlapping peptides from CMV pp65 (c) or HIV Gag (d).
