Table 1.
Characteristics of the normal (NI) and hyperinsulinaemic (HI) participants at the screening visit.
| NI | HI | P-value | |
|---|---|---|---|
| Age (y) | 35.9 ± 3.8 | 37.5 ± 2.2 | 0.72 |
| M:F | 4 : 5 | 2 : 6 | |
| BMI (kg/m2) | 25.4 ± 1.5 | 28.7 ± 0.7 | 0.07 |
| Waist Circumference (cm) | 87.7 ± 2.7 | 95.2 ± 1.5 | 0.03 |
| Systolic blood pressure (mm Hg) | 109 ± 3 | 119 ± 3 | 0.05 |
| Diastolic blood pressure (mm Hg) | 68 ± 3 | 78 ± 4 | 0.08 |
| Glucose (mmol/L) | 5.0 ± 0.1 | 5.1 ± 0.2 | 0.68 |
| Insulin (pmol/L) | 29.4 ± 2.0 | 75.4 ± 12.7 | 0.01 |
| HCT (L/L) | 0.39 ± 0.01 | 0.40 ± 0.01 | 0.85 |
| AST (U/L) | 18.9 ± 1.3 | 21.8 ± 1.7 | 0.22 |
| CRP (mg/L) | 2.5 ± 1.8 | 2.9 ± 0.7 | 0.81 |
| Cholesterol (mmol/L) | 4.7 ± 0.2 | 5.2 ± 0.5 | 0.34 |
| Triglycerides (mmol/L) | 0.91 ± 0.12 | 1.63 ± 0.3 | 0.05 |
| HDL (mmol/L) | 1.42 ± 0.06 | 1.08 ± 0.08 | 0.01 |
| TC/HDL | 3.33 ± 0.18 | 4.86 ± 0.32 | 0.00 |
| LDL (mmol/L) | 2.84 ± 0.21 | 3.38 ± 0.32 | 0.20 |
Data are presented as mean ± SEM. Abbreviations: HCT, hematocrit; AST, aspartate transaminase; CRP, C-reactive protein; TC, total cholesterol; HDL, high density lipoprotein; LDL, low density lipoprotein.