Table 3.
Costs and Benefit [mean (95% credibility interval)] per 10,000 admissions with baseline MRSA prevalence on admission, a 6-day attributable MRSA length of stay, and an extreme contact precaution efficacy estimate (0.03 infections averted per MRSA colonized patient isolated)
| Chromogenic Agar Screening | PCR Screening | |||||
|---|---|---|---|---|---|---|
| Total number of MRSA colonized patients | 953 (780 - 1,140) | 946 (770 - 1,140) | ||||
| Body Site(s) Tested | Nares | Nares/Oropharynx | Multi Site Swab | Nares | Nares/Oropharynx | Multi Site Swab |
| Patients Correctly Identified as Colonized | 542 (410 - 680) | 680 (530 - 820) | 786 (630 - 950) | 575 (430 - 730) | 720 (560 - 890) | 824 (660 - 1,000) |
| Patients Placed in Contact Precautions | 622 (470 - 760) | 758 (590 - 920) | 863 (690 - 1,040) | 915 (740 - 1,110) | 1,054 (870 - 1,250) | 1,155 (960 - 1,370) |
| Intervention Cost | $251,555 (205,554 - 299,868) | $304,142 (250,214 - 353,933) | $346,774 (292,645 - 402,702) | $571,564 (515,439 - 632,775) | $625,012 (566,246 - 690,416) | $666,295 (601,959 - 733,215) |
| Swabs | $10,000 | $20,000 | $30,000 | $10,000 | $20,000 | $30,000 |
| Testing* | $46,876 (46,740 - 47,006) | $46,876 (46,740 - 47,006) | $46,876 (46,740 - 47,006) | $275,455 (275,165 - 275,715) | $275,455 (275,165 - 275,715) | $275,455 (275,165 - 275,715) |
| Gloves | $11,583 (8,841 - 14,452) | $14,119 (10,941 - 17,159) | $16,061 (12,867 - 19,366) | $17,025 (13,750 - 20,763) | $19,610 (16,127 - 23,420) | $21,475 (17,658 - 25,422) |
| Gowns | $117,659 (90,020 - 146,384) | $143,386 (110,867 - 173,361) | $163,125 (130,381 - 196,500) | $172,913 (139,405 - 209,892) | $199,178 (164,097 - 238,282) | $218,074 (179,641 - 258,298) |
| Nursing Time | $65,437 (49,952 - 82,027) | $79,762 (61,666 - 96,407) | $90,713 (72,656 - 109,830) | $96,171 (77,118 - 116,404) | $110,768 (90,856 - 133,000) | $121,293 (99,495 - 143,780) |
| MRSA Infections Avoided | 16 (12 - 20) | 20 (16 - 25) | 24 (19 - 29) | 18 (13 - 22) | 22 (17 - 27) | 25 (20 - 30) |
| Cost Averted | $147,777 (110,142 - 186,002) | $143,386 (110,867 - 173,361) | $163,125 (130,381 - 196,830) | $158,993 (121,130 - 199,233) | $196,630 (152,043 - 243,162) | $223,685 (176,000 - 272,216) |
| Cost-Benefit^ | −$103,778 (−$83,491 - −$126,252) | −$119,474 (−$97,905 - −$143,518) | −$133,349 (−$110,865 - −$157,160) | −$412,571 (−$376,833 - −$452,963) | −$428,381 (−$392,508 - −$469,522) | −$442,609 (−$405,763 - −$481,495) |
| Gain vs. Loss | Loss | Loss | Loss | Loss | Loss | Loss |
*
Includes test materials and technician labor to process sample; Multiple samples were tested by splitting Chromogenic Agar plates and combining samples for PCR runs
^
Negative values indicate a economic loss to hospital given a $0 break-even threshold