Table 5.

Associations of OSA risk^* with blood and airway inflammatory markers in subjects with asthma.

	Univariate Analyses†		Multivariate Analyses†‡
	Parameter estimate (95% CI)	p-value	Parameter estimate (95% CI)	p-value
Log IgE	-0.04 (-0.16, 0.07)	0.42	-0.12 (-0.28, 0.03)	0.11
Blood eos count	-0.001 (-0.04, 0.03)	0.94	-0.004 (-0.05, 0.04)	0.87
Blood Eosinophils%	-0.12 (-0.55, 0.32)	0.60	0.01 (-0.57, 0.59)	0.97
eNO	-3.43 (-10.21, 3.35)	0.32	-0.30 (-9.14, 8.54)	0.94
Sputum Eosinophils %	0.61 (-1.24, 2.45)	0.52	0.28 (-2.27, 2.82)	0.83
Sputum PMNs%	5.68 (1.76, 9.60)	0.005	7.78 (2.33, 13.22)	0.006

^*Sleep Apnea scale of the Sleep Disorders Questionnaire score normalized by its standard deviation.

^†Analyses used general linear models.

^‡Adjusted for obesity, smoking history (yes/no) and any (inhaled or systemic) current corticosteroid use.

Abbreviations: CI= confidence interval; eNO=fraction of exhaled nitric oxide; PMNs=polymorphonuclear neutrophils.