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. Author manuscript; available in PMC: 2016 Aug 15.
Published in final edited form as: J Neurosci Methods. 2015 May 18;251:120–129. doi: 10.1016/j.jneumeth.2015.05.006

Figure 5. HPLC-EC studies of DA turnover (DOPAC + HVA)/DA in unilateral (right) 6-OHDA lesioned rats after repeated intranasal administration of DNSP-11 or vehicle.

Figure 5

DNSP-11 treatment significantly decreased DA turnover in the ipsilateral (right/lesioned) striatum from 0.884 ± 0.074 to 0.538 ± 0.062 ng/g at 5 weeks in 6-OHDA lesioned rats (green diamonds) compared to vehicle (open circles). Data were analyzed using a one-way ANOVA (F(3,24) = 24.62, p < 0.0001) with Bonferroni’s post hoc test **p < 0.01. Data presented as mean ± SEM, n = 8 vehicle, n = 6 DNSP-11.