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Clinical Ω-loop variants of the SHV and KPC β-lactamasesa
| Enzyme | Amino acid substitution |
|---|---|
| SHV-6 | D179A |
| SHV-8 | D179N |
| SHV-16 | 5 amino acid duplication at E166 |
| SHV-19, -20, -21 | L173F |
| SHV-24 | D179G |
| SHV-51 | G175A |
| SHV-57 | L169R |
| SHV-79 | A172V |
| SHV-111 | P174S |
| SHV-143 | R164L |
| KPC-12 | L169M |
aObtained from the Lahey website: http://www.lahey.org/Studies.
