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. 2015 May 9;70(8):2223–2227. doi: 10.1093/jac/dkv114

Figure 1.

Figure 1.

The XbaI PFGE-based dendrogram for the 32 E. coli ST131 isolates. The dendrogram was generated according to the unweighted pair group method based on Dice coefficients. O types, serogroup; FQ, fluoroquinolone phenotype (R, resistant; S, susceptible); fimH, allele of fimH (type 1 fimbrial adhesin); gyrA/parC, allele of gyrA and parC (encoding DNA gyrase and topoisomerase, respectively); 1/1b, gyrA1 (WT) combined with parC1b (one silent mutation); 1A/1b, gyrA1A (one replacement mutation, Ser83Leu) combined with parC1b; 1AB/3A, gyrA1AB (two replacement mutations, Ser83Leu and Asp87Asn) combined with parC3A (a recombined variant containing one replacement mutation Ser80Ile); 1AB/1aAB, gyrA1AB combined with parC1aAB (parC1a plus the replacement mutations Ser80Ile and Glu84Val). The 32 ST131 isolates formed one large group at the 64% similarity level. They comprised 15 PFGE groups (defined at ≥85% similarity).