Table I.
Summary of OT-I transfer experimentsa
| recipient mice | source | # of OT-I transferred | genotype of OT-I | Virus | pfu | # of mice | # of rejectorsb | % rejected |
|---|---|---|---|---|---|---|---|---|
| B6.SJL (CD45.1+) | Taconic | 600+ | CD45.2 | GFP-SL8 | 2×105 | 33 | 28 | 84.85% |
| B6.SJL (CD45.1+) | Taconic | 600 | CD45.2 | K181-ova | 2×105 | 7 | 6 | 85.71% |
| B6.SJL (CD45.1+) | Jackson | 600+ | CD45.2 & CD45.1/.2 | GFP-SL8 | 2×105 | 25 | 4 | 16% |
| CD45.1/.2 | in house | 600 | CD45.2 | GFP-SL8 | 2×105 | 19 | 7 | 36.84% |
| B6 (CD45.2+) | Jackson | 6 - 3,600 | CD45.1/.2 | GFP-SL8 | 2×105 | 32 | 11 | 34.38% |
| B6 (CD45.2+) | Jackson | 600 | CD45.1/.2 | GFP-SL8 | 2×104 | 4 | 3 | 75% |
| B6 (CD45.2+) | Jackson | 600 | CD45.1/.2 | GFP-SL8 | 50 | 7 | 2 | 28.57% |
| μMT (CD45.2+) | Jackson | 600 | CD45.1/.2 | GFP-SL8 | 2×105 | 6 | 4 | 66.67% |
a
Shown is a summary of OT-I transfer experiments including the genotype of the donor and recipient animals, the origin of recipient mice, the number and genotype of OT-Is transferred, the virus and titer used to infect recipients and the number and frequency of mice that retained or lost their OT-Is.
b
Experiments were not always carried for the same amount of time. It is possible that more mice would have lost OT-Is given more time.