Skip to main content
. Author manuscript; available in PMC: 2015 Jul 13.
Published in final edited form as: Periodontol 2000. 2014 Feb;64(1):57–80. doi: 10.1111/prd.12002

Table 1.

The source cell, location and associated bacteria for toll-like receptors.

Receptor Location Cells Bacteria
Toll-like receptor 1 Cell membrane Myeloid dendritic cells, monocytes Not specified
Toll-like receptor 2 Cell membrane Monocytes, natural killer cells, myeloid dendritic cells,mast cells, T-cells, epithelial cells Porphyromonas gingivalis
Escherichia coli
Tannerella forsythia
Prevotella intermedia
Prevotella nigrescens
Treponema denticola
Toll-like receptor 3 Intracellular Myeloid dendritic cells, natural killer cells, epithelial cells Not specified
Toll-like receptor 4 Cell membrane Monocytes, mast cells, neutrophils, T cells, epithelial cells, endothelial cells Aggregatibacter actinomycetemcomitans,
Veillonella parvula
Toll-like receptor 5 Cell membrane Monocytes, natural killer cells, myeloid dendritic cells epithelial cells Not specified
Toll-like receptor 6 Cell membrane Myeloid cells, mast cells, B-cells, myeloid dendritic cells Escherichia coli
Toll-like receptor 7 Intracellular Plasmacytoid dendritic cells, B-cells, eosinophils Not specified
Toll-like receptor 8 Intracellular Natural killer cells, T-cells, myeloid cells, myeloid dendritic cells Not specified
Toll-like receptor 9 Intracellular Plasmacytoid dendritic cells, B-cells, natural killer cells Porphyromonas gingivalis
Aggregatibacter actinomycetemcomitans
Toll-like receptor 10 Cell membrane B-cells, plasmacytoid dendritic cells, myeloid dendritic cells Not specified
Toll-like receptor 11 Intracellular Macrophages, dendritic cells, epithelial cells Not specified