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. 2015 Jul 14;9:180. doi: 10.3389/fnbeh.2015.00180

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Copyright © 2015 Garcia-Alvarez, Shetty, Lu, Yap, Oh-Hora, Sajikumar, Bichler and Fivaz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Unaltered spatial working memory in Stim cKO mutant mice. (A–C) Percentage of correct choices in the radial arm maze plotted for each training day as the mean ± SEM. Performance reaches a plateau at 80% correct choices (dashed line) around the 10th day of training. (A) Stim1^fl/fl;Cre⁺ (n = 12) and Cre⁻ (n = 12) mice. (B) Stim2^fl/fl;Cre⁺(n = 12) and Cre⁻ (n = 12) mice. (C) Stim1^fl/fl/Stim2^fl^/^fl;Cre⁺ (n = 7) and Cre⁻ (n = 10) mice. Two Way ANOVA showed a learning effect (p < 0.001 with “days” as within factor) but no genotype effect (p > 0.05, “genotype” as in between factor).