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. 2015 Jul 14;9:180. doi: 10.3389/fnbeh.2015.00180

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Copyright © 2015 Garcia-Alvarez, Shetty, Lu, Yap, Oh-Hora, Sajikumar, Bichler and Fivaz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of the Stim genes on PKA signaling. (A) Phospho-immunoblots of pSer845-GluA1, pSer133-CREB, and pSer1928-Cav1.2 in hippocampus (hippo) and cerebellum (cereb) harvested from the three Stim cKO (Cre⁺) lines and their control (Cre⁻) littermates. (B) Quantification of pSer845-GluA1, pSer133-CREB, and pSer1928-Cav1.2 levels (n = 3 for each group). Phospho-protein signals are normalized within each Stim genotype to the Cre⁻ group. Blot exposures were adjusted for optimal comparison of phospho-signals in Cre⁻ and Cre⁺ groups and thus do not accurately reflect relative levels of phosphoproteins in the different Stim lines. Means ± SD are shown. ^***p < 0.001, t-test.